SOX10 is abnormally expressed in aganglionic bowel of Hirschsprung's disease infants
نویسندگان
چکیده
منابع مشابه
SOX10 is abnormally expressed in aganglionic bowel of Hirschsprung's disease infants.
BACKGROUND The primary pathology of Hirschsprung's disease (HD) is a congenital absence of ganglion cells in the caudal most gut. The spastic aganglionic bowel is often innervated by a network of hypertrophied nerve fibres. Recently, mutations of SOX10 have been identified in patients with HD but only in those with Waardenburg-Shah syndrome. AIMS To understand the molecular basis for the path...
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ژورنال
عنوان ژورنال: Gut
سال: 2001
ISSN: 0017-5749
DOI: 10.1136/gut.49.2.220